This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1jxh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:42, 7 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1jxh.png|left|200px]]
 
-
{{STRUCTURE_1jxh| PDB=1jxh | SCENE= }}
+
==4-Amino-5-hydroxymethyl-2-methylpyrimidine Phosphate Kinase from Salmonella typhimurium==
-
 
+
<StructureSection load='1jxh' size='340' side='right'caption='[[1jxh]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-
===4-Amino-5-hydroxymethyl-2-methylpyrimidine Phosphate Kinase from Salmonella typhimurium===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1jxh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JXH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JXH FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_11839308}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jxh OCA], [https://pdbe.org/1jxh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jxh RCSB], [https://www.ebi.ac.uk/pdbsum/1jxh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jxh ProSAT]</span></td></tr>
-
[[1jxh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JXH OCA].
+
</table>
-
 
+
== Function ==
-
==Reference==
+
[https://www.uniprot.org/uniprot/THID_SALTY THID_SALTY] Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P (By similarity).
-
<ref group="xtra">PMID:011839308</ref><references group="xtra"/>
+
== Evolutionary Conservation ==
-
[[Category: Phosphomethylpyrimidine kinase]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
+
Check<jmol>
-
[[Category: Begley, T P.]]
+
<jmolCheckbox>
-
[[Category: Bennett, E M.]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jx/1jxh_consurf.spt"</scriptWhenChecked>
-
[[Category: Cheng, G.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Ealick, S E.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Kinase]]
+
</jmolCheckbox>
-
[[Category: Phophorylation]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jxh ConSurf].
-
[[Category: Ribokinase family]]
+
<div style="clear:both"></div>
-
[[Category: Thid]]
+
__TOC__
-
[[Category: Transferase]]
+
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
 +
[[Category: Begley TP]]
 +
[[Category: Bennett EM]]
 +
[[Category: Cheng G]]
 +
[[Category: Ealick SE]]

Current revision

4-Amino-5-hydroxymethyl-2-methylpyrimidine Phosphate Kinase from Salmonella typhimurium

PDB ID 1jxh

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools