1jqw

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[[Image:1jqw.png|left|200px]]
 
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{{STRUCTURE_1jqw| PDB=1jqw | SCENE= }}
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==THE 2.3 ANGSTROM RESOLUTION STRUCTURE OF BACILLUS SUBTILIS LUXS/HOMOCYSTEINE COMPLEX==
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<StructureSection load='1jqw' size='340' side='right'caption='[[1jqw]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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===THE 2.3 ANGSTROM RESOLUTION STRUCTURE OF BACILLUS SUBTILIS LUXS/HOMOCYSTEINE COMPLEX===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1jqw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JQW FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11601850}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HCS:2-AMINO-4-MERCAPTO-BUTYRIC+ACID'>HCS</scene>, <scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jqw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jqw OCA], [https://pdbe.org/1jqw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jqw RCSB], [https://www.ebi.ac.uk/pdbsum/1jqw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jqw ProSAT]</span></td></tr>
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[[1jqw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQW OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/LUXS_BACSU LUXS_BACSU] Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).[HAMAP-Rule:MF_00091]
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<ref group="xtra">PMID:011601850</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jq/1jqw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jqw ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: S-ribosylhomocysteine lyase]]
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[[Category: Large Structures]]
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[[Category: Baker, P J.]]
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[[Category: Baker PJ]]
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[[Category: Blackburn, G M.]]
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[[Category: Blackburn GM]]
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[[Category: Cox, A G.]]
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[[Category: Cox AG]]
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[[Category: Das, S K.]]
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[[Category: Das SK]]
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[[Category: Foster, S J.]]
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[[Category: Foster SJ]]
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[[Category: Hartley, A.]]
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[[Category: Hartley A]]
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[[Category: Horsburgh, M J.]]
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[[Category: Horsburgh MJ]]
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[[Category: McCleod, C W.]]
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[[Category: McCleod CW]]
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[[Category: Mekhalfia, A.]]
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[[Category: Mekhalfia A]]
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[[Category: Rice, D W.]]
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[[Category: Rice DW]]
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[[Category: Ruzheinikov, S N.]]
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[[Category: Ruzheinikov SN]]
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[[Category: Sedelnikova, S E.]]
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[[Category: Sedelnikova SE]]
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[[Category: Autoinducer synthesis]]
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[[Category: Signaling protein]]
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Current revision

THE 2.3 ANGSTROM RESOLUTION STRUCTURE OF BACILLUS SUBTILIS LUXS/HOMOCYSTEINE COMPLEX

PDB ID 1jqw

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