1k2h
From Proteopedia
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| - | [[Image:1k2h.png|left|200px]] | ||
| - | + | ==Three-dimensional Solution Structure of apo-S100A1.== | |
| + | <StructureSection load='1k2h' size='340' side='right'caption='[[1k2h]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1k2h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K2H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K2H FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k2h OCA], [https://pdbe.org/1k2h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k2h RCSB], [https://www.ebi.ac.uk/pdbsum/1k2h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k2h ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/S10A1_RAT S10A1_RAT] Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k2/1k2h_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k2h ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[S100 proteins 3D structures|S100 proteins 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| - | [[ | + | |
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| - | < | + | |
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| - | [[Category: Baldisseri | + | [[Category: Baldisseri DM]] |
| - | [[Category: Hamilton | + | [[Category: Hamilton SM]] |
| - | [[Category: Inman | + | [[Category: Inman KG]] |
| - | [[Category: Landar | + | [[Category: Landar A]] |
| - | [[Category: Nizner | + | [[Category: Nizner P]] |
| - | [[Category: Rustandi | + | [[Category: Rustandi RR]] |
| - | [[Category: Weber | + | [[Category: Weber DJ]] |
| - | [[Category: Zimmer | + | [[Category: Zimmer DB]] |
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Current revision
Three-dimensional Solution Structure of apo-S100A1.
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