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1jj8

From Proteopedia

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[[Image:1jj8.png|left|200px]]
 
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{{STRUCTURE_1jj8| PDB=1jj8 | SCENE= }}
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==Testing the Water-Mediated HIN Recombinase DNA Recognition by Systematic Mutations==
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<StructureSection load='1jj8' size='340' side='right'caption='[[1jj8]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1jj8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JJ8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5IU:5-IODO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>5IU</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jj8 OCA], [https://pdbe.org/1jj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jj8 RCSB], [https://www.ebi.ac.uk/pdbsum/1jj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jj8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HIN_SALTY HIN_SALTY] A DNA fragment of approximately 900 base pairs, adjacent to the fljB (H2) gene, which specifies the synthesis of phase-2 flagellin, can exist in either orientation with respect to fljB. The orientation of the inversion region controls expression of fljB. The hin gene occupies about two-thirds of the inversion region; it is required for the inversion of the fljB controlling region.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jj/1jj8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jj8 ConSurf].
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<div style="clear:both"></div>
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===Testing the Water-Mediated HIN Recombinase DNA Recognition by Systematic Mutations===
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==See Also==
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*[[Resolvase 3D structures|Resolvase 3D structures]]
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{{ABSTRACT_PUBMED_11847127}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[1jj8]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JJ8 OCA].
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Chiu TK]]
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==Reference==
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[[Category: Dickerson RE]]
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<ref group="xtra">PMID:011847127</ref><references group="xtra"/>
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[[Category: Johnson RC]]
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[[Category: Chiu, T K.]]
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[[Category: Sohn C]]
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[[Category: Dickerson, R E.]]
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[[Category: Johnson, R C.]]
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[[Category: Sohn, C.]]
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[[Category: Dna binding protein-dna complex]]
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[[Category: Hin recombinase]]
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[[Category: I4 form 2]]
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[[Category: Protein-dna complex]]
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[[Category: Water-mediated recognition]]
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Current revision

Testing the Water-Mediated HIN Recombinase DNA Recognition by Systematic Mutations

PDB ID 1jj8

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