1jvi

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[[Image:1jvi.png|left|200px]]
 
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{{STRUCTURE_1jvi| PDB=1jvi | SCENE= }}
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==THE 2.2 ANGSTROM RESOLUTION STRUCTURE OF BACILLUS SUBTILIS LUXS/RIBOSILHOMOCYSTEINE COMPLEX==
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<StructureSection load='1jvi' size='340' side='right'caption='[[1jvi]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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===THE 2.2 ANGSTROM RESOLUTION STRUCTURE OF BACILLUS SUBTILIS LUXS/RIBOSILHOMOCYSTEINE COMPLEX===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1jvi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JVI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JVI FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11601850}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HCS:2-AMINO-4-MERCAPTO-BUTYRIC+ACID'>HCS</scene>, <scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene>, <scene name='pdbligand=RHC:5-(3-AMINO-4,4-DIHYROXY-BUTYLSULFANYLMETHYL)-TETRAHYDRO-FURAN-2,3,4-TRIOL'>RHC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jvi OCA], [https://pdbe.org/1jvi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jvi RCSB], [https://www.ebi.ac.uk/pdbsum/1jvi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jvi ProSAT]</span></td></tr>
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[[1jvi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JVI OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/LUXS_BACSU LUXS_BACSU] Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).[HAMAP-Rule:MF_00091]
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<ref group="xtra">PMID:011601850</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jv/1jvi_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jvi ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Baker, P J.]]
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[[Category: Large Structures]]
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[[Category: Blackburn, G M.]]
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[[Category: Baker PJ]]
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[[Category: Cox, A G.]]
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[[Category: Blackburn GM]]
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[[Category: Das, S K.]]
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[[Category: Cox AG]]
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[[Category: Foster, S J.]]
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[[Category: Das SK]]
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[[Category: Hartley, A.]]
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[[Category: Foster SJ]]
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[[Category: Horsburgh, M J.]]
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[[Category: Hartley A]]
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[[Category: McCleod, C W.]]
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[[Category: Horsburgh MJ]]
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[[Category: Mekhalfia, A.]]
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[[Category: McCleod CW]]
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[[Category: Rice, D W.]]
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[[Category: Mekhalfia A]]
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[[Category: Ruzheinikov, S N.]]
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[[Category: Rice DW]]
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[[Category: Sedelnikova, S E.]]
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[[Category: Ruzheinikov SN]]
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[[Category: Autoinducer synthesis]]
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[[Category: Sedelnikova SE]]
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[[Category: Signaling protein]]
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Current revision

THE 2.2 ANGSTROM RESOLUTION STRUCTURE OF BACILLUS SUBTILIS LUXS/RIBOSILHOMOCYSTEINE COMPLEX

PDB ID 1jvi

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