1jx7

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[[Image:1jx7.png|left|200px]]
 
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{{STRUCTURE_1jx7| PDB=1jx7 | SCENE= }}
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==Crystal structure of ychN protein from E.coli==
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<StructureSection load='1jx7' size='340' side='right'caption='[[1jx7]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1jx7]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JX7 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jx7 OCA], [https://pdbe.org/1jx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jx7 RCSB], [https://www.ebi.ac.uk/pdbsum/1jx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jx7 ProSAT], [https://www.topsan.org/Proteins/BSGC/1jx7 TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/YCHN_ECOLI YCHN_ECOLI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jx/1jx7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jx7 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The crystal structure of a conserved hypothetical protein from Escherichia coli has been determined using X-ray crystallography. The protein belongs to the Cluster of Orthologous Group COG1553 (National Center for Biotechnology Information database, NLM, NIH), for which there was no structural information available until now. Structural homology search with DALI algorism indicated that this protein has a new fold with no obvious similarity to those of other proteins with known three-dimensional structures. The protein quaternary structure consists of a dimer of trimers, which makes a characteristic cylinder shape. There is a large closed cavity with approximate dimensions of 16 A x 16 A x 20 A in the center of the hexameric structure. Six putative active sites are positioned along the equatorial surface of the hexamer. There are several highly conserved residues including two possible functional cysteines in the putative active site. The possible molecular function of the protein is discussed.
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===Crystal structure of ychN protein from E.coli===
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Crystal structure of a conserved hypothetical protein from Escherichia coli.,Shin DH, Yokota H, Kim R, Kim SH J Struct Funct Genomics. 2002;2(1):53-66. PMID:12836674<ref>PMID:12836674</ref>
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{{ABSTRACT_PUBMED_12836674}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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==About this Structure==
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<div class="pdbe-citations 1jx7" style="background-color:#fffaf0;"></div>
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[[1jx7]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JX7 OCA].
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== References ==
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<references/>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:012836674</ref><references group="xtra"/>
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: BSGC, Berkeley Structural Genomics Center.]]
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[[Category: Large Structures]]
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[[Category: Kim, R.]]
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[[Category: Kim R]]
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[[Category: Kim, S H.]]
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[[Category: Kim S-H]]
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[[Category: Shin, D H.]]
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[[Category: Shin DH]]
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[[Category: Yokota, H.]]
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[[Category: Yokota H]]
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[[Category: Berkeley structural genomics center]]
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[[Category: Bsgc structure funded by nih]]
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[[Category: Hexamer]]
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[[Category: New fold]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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[[Category: Unknown function]]
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Current revision

Crystal structure of ychN protein from E.coli

PDB ID 1jx7

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