1je3

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[[Image:1je3.png|left|200px]]
 
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{{STRUCTURE_1je3| PDB=1je3 | SCENE= }}
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==Solution Structure of EC005 from Escherichia coli==
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<StructureSection load='1je3' size='340' side='right'caption='[[1je3]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1je3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JE3 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1je3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1je3 OCA], [https://pdbe.org/1je3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1je3 RCSB], [https://www.ebi.ac.uk/pdbsum/1je3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1je3 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/YEDF_ECOLI YEDF_ECOLI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/1je3_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1je3 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The influx of genomic sequence information has led to the concept of structural proteomics, the determination of protein structures on a genome-wide scale. Here we describe an approach to structural proteomics of small proteins using NMR spectroscopy. Over 500 small proteins from several organisms were cloned, expressed, purified, and evaluated by NMR. Although there was variability among proteomes, overall 20% of these proteins were found to be readily amenable to NMR structure determination. NMR sample preparation was centralized in one facility, and a distributive approach was used for NMR data collection and analysis. Twelve structures are reported here as part of this approach, which allowed us to infer putative functions for several conserved hypothetical proteins.
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===Solution Structure of EC005 from Escherichia coli===
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An NMR approach to structural proteomics.,Yee A, Chang X, Pineda-Lucena A, Wu B, Semesi A, Le B, Ramelot T, Lee GM, Bhattacharyya S, Gutierrez P, Denisov A, Lee CH, Cort JR, Kozlov G, Liao J, Finak G, Chen L, Wishart D, Lee W, McIntosh LP, Gehring K, Kennedy MA, Edwards AM, Arrowsmith CH Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1825-30. PMID:11854485<ref>PMID:11854485</ref>
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{{ABSTRACT_PUBMED_11854485}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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==About this Structure==
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<div class="pdbe-citations 1je3" style="background-color:#fffaf0;"></div>
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[[1je3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JE3 OCA].
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== References ==
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<references/>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:011854485</ref><references group="xtra"/>
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Arrowsmith, C.]]
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[[Category: Large Structures]]
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[[Category: Denisov, A.]]
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[[Category: Arrowsmith C]]
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[[Category: Gehring, K.]]
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[[Category: Denisov A]]
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[[Category: Gutierrez, P.]]
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[[Category: Gehring K]]
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[[Category: Kozlov, G.]]
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[[Category: Gutierrez P]]
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[[Category: Yee, A.]]
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[[Category: Kozlov G]]
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[[Category: Mixed alpha-beta structure]]
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[[Category: Yee A]]
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[[Category: Structural genomic]]
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Current revision

Solution Structure of EC005 from Escherichia coli

PDB ID 1je3

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