This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1mdb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1mdb" [edit=sysop:move=sysop])
Current revision (07:43, 14 February 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1mdb.png|left|200px]]
 
-
{{STRUCTURE_1mdb| PDB=1mdb | SCENE= }}
+
==CRYSTAL STRUCTURE OF DhbE IN COMPLEX WITH DHB-ADENYLATE==
-
 
+
<StructureSection load='1mdb' size='340' side='right'caption='[[1mdb]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
-
===CRYSTAL STRUCTURE OF DhbE IN COMPLEX WITH DHB-ADENYLATE===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1mdb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MDB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MDB FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_12221282}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=DBH:2,3-DIHYDROXY-BENZOIC+ACID'>DBH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mdb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mdb OCA], [https://pdbe.org/1mdb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mdb RCSB], [https://www.ebi.ac.uk/pdbsum/1mdb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mdb ProSAT]</span></td></tr>
-
[[1mdb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MDB OCA].
+
</table>
-
 
+
== Function ==
-
==Reference==
+
[https://www.uniprot.org/uniprot/DHBE_BACSU DHBE_BACSU] Activation of the carboxylate group of 2,3-dihydroxy-benzoate (DHB), via ATP-dependent PPi exchange reactions, to the acyladenylate.
-
<ref group="xtra">PMID:012221282</ref><references group="xtra"/>
+
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/md/1mdb_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mdb ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
-
[[Category: Kessler, N.]]
+
[[Category: Large Structures]]
-
[[Category: Marahiel, M A.]]
+
[[Category: Kessler N]]
-
[[Category: May, J J.]]
+
[[Category: Marahiel MA]]
-
[[Category: Stubbs, M T.]]
+
[[Category: May JJ]]
-
[[Category: Adenylation domain]]
+
[[Category: Stubbs MT]]
-
[[Category: Antibiotic biosynthesis]]
+
-
[[Category: Ligase]]
+
-
[[Category: Peptide synthetase]]
+
-
[[Category: Siderophore formation]]
+

Current revision

CRYSTAL STRUCTURE OF DhbE IN COMPLEX WITH DHB-ADENYLATE

PDB ID 1mdb

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools