1n0i

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1n0i" [edit=sysop:move=sysop])
Current revision (07:50, 14 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1n0i.png|left|200px]]
 
-
{{STRUCTURE_1n0i| PDB=1n0i | SCENE= }}
+
==Crystal Structure of Ferrochelatase with Cadmium bound at active site==
 +
<StructureSection load='1n0i' size='340' side='right'caption='[[1n0i]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[1n0i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N0I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N0I FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n0i OCA], [https://pdbe.org/1n0i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n0i RCSB], [https://www.ebi.ac.uk/pdbsum/1n0i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n0i ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CPFC_BACSU CPFC_BACSU] Involved in coproporphyrin-dependent heme b biosynthesis (PubMed:25646457, PubMed:25908396). Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III (PubMed:25646457, PubMed:25908396). It can also insert iron into protoporphyrin IX (PubMed:1459957, PubMed:8119288, PubMed:21052751, PubMed:25646457). Has weaker activity with 2,4 disulfonate, deuteroporphyrin and 2,4 hydroxyethyl (PubMed:25646457, PubMed:12761666). In vitro, can also use Zn(2+) or Cu(2+) (PubMed:8119288, PubMed:16140324, PubMed:21052751, PubMed:12761666).<ref>PMID:12761666</ref> <ref>PMID:1459957</ref> <ref>PMID:16140324</ref> <ref>PMID:21052751</ref> <ref>PMID:25646457</ref> <ref>PMID:25826316</ref> <ref>PMID:25908396</ref> <ref>PMID:8119288</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n0/1n0i_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n0i ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal Structure of Ferrochelatase with Cadmium bound at active site===
+
==See Also==
-
 
+
*[[Ferrochelatase 3D structures|Ferrochelatase 3D structures]]
-
{{ABSTRACT_PUBMED_12761666}}
+
== References ==
-
 
+
<references/>
-
==About this Structure==
+
__TOC__
-
[[1n0i]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N0I OCA].
+
</StructureSection>
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:012761666</ref><references group="xtra"/>
+
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
-
[[Category: Ferrochelatase]]
+
[[Category: Large Structures]]
-
[[Category: Al-Karadaghi, S.]]
+
[[Category: Al-Karadaghi S]]
-
[[Category: Fodje, M N.]]
+
[[Category: Fodje MN]]
-
[[Category: Hansson, A.]]
+
[[Category: Hansson A]]
-
[[Category: Hansson, M.]]
+
[[Category: Hansson M]]
-
[[Category: Lecerof, D.]]
+
[[Category: Lecerof D]]
-
[[Category: Leon, R A.]]
+
[[Category: Leon RA]]
-
[[Category: Olsson, U.]]
+
[[Category: Olsson U]]
-
[[Category: Ryde, U.]]
+
[[Category: Ryde U]]
-
[[Category: Sigfridsson, E.]]
+
[[Category: Sigfridsson E]]
-
[[Category: Lyase]]
+
-
[[Category: Pi-helix]]
+

Current revision

Crystal Structure of Ferrochelatase with Cadmium bound at active site

PDB ID 1n0i

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1n0i"
Personal tools