1mr7
From Proteopedia
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- | [[Image:1mr7.png|left|200px]] | ||
- | + | ==Crystal Structure of Streptogramin A Acetyltransferase== | |
- | + | <StructureSection load='1mr7' size='340' side='right'caption='[[1mr7]], [[Resolution|resolution]] 1.80Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1mr7]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecium Enterococcus faecium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MR7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MR7 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mr7 OCA], [https://pdbe.org/1mr7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mr7 RCSB], [https://www.ebi.ac.uk/pdbsum/1mr7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mr7 ProSAT]</span></td></tr> | |
- | == | + | </table> |
- | [[1mr7]] is a 6 chain structure with sequence from [ | + | == Function == |
- | + | [https://www.uniprot.org/uniprot/VATD_ENTFC VATD_ENTFC] Inactivates the A compounds of streptogramin antibiotics by acetylation, thus providing resistance to these antibiotics. | |
- | == | + | == Evolutionary Conservation == |
- | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mr/1mr7_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mr7 ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Enterococcus faecium]] | [[Category: Enterococcus faecium]] | ||
- | [[Category: Courvalin | + | [[Category: Large Structures]] |
- | [[Category: Kehoe | + | [[Category: Courvalin P]] |
- | [[Category: Murray | + | [[Category: Kehoe LE]] |
- | [[Category: Rafferty | + | [[Category: Murray IA]] |
- | [[Category: Snidwongse | + | [[Category: Rafferty JB]] |
- | + | [[Category: Snidwongse J]] | |
- | + |
Current revision
Crystal Structure of Streptogramin A Acetyltransferase
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