1mcj

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[[Image:1mcj.png|left|200px]]
 
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{{STRUCTURE_1mcj| PDB=1mcj | SCENE= }}
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==PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS==
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<StructureSection load='1mcj' size='340' side='right'caption='[[1mcj]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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===PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1mcj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MCJ FirstGlance]. <br>
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{{ABSTRACT_PUBMED_8346191}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DPN:D-PHENYLALANINE'>DPN</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mcj OCA], [https://pdbe.org/1mcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mcj RCSB], [https://www.ebi.ac.uk/pdbsum/1mcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mcj ProSAT]</span></td></tr>
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[[1mcj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MCJ OCA].
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</table>
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== Evolutionary Conservation ==
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==Reference==
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[[Image:Consurf_key_small.gif|200px|right]]
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<ref group="xtra">PMID:008346191</ref><references group="xtra"/>
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mc/1mcj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mcj ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Edmundson, A B.]]
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[[Category: Large Structures]]
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[[Category: Fan, Z C.]]
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[[Category: Edmundson AB]]
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[[Category: Guddat, L W.]]
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[[Category: Fan Z-C]]
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[[Category: Harris, D L.]]
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[[Category: Guddat LW]]
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[[Category: Immunoglobulin]]
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[[Category: Harris DL]]

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PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS

PDB ID 1mcj

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