1lr5

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[[Image:1lr5.png|left|200px]]
 
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{{STRUCTURE_1lr5| PDB=1lr5 | SCENE= }}
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==Crystal structure of auxin binding protein==
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<StructureSection load='1lr5' size='340' side='right'caption='[[1lr5]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1lr5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LR5 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lr5 OCA], [https://pdbe.org/1lr5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lr5 RCSB], [https://www.ebi.ac.uk/pdbsum/1lr5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lr5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ABP1_MAIZE ABP1_MAIZE] This is probably a receptor for the plant hormone auxin.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lr/1lr5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lr5 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The structure of auxin-binding protein 1 (ABP1) from maize has been determined at 1.9 A resolution, revealing its auxin-binding site. The structure confirms that ABP1 belongs to the ancient and functionally diverse germin/seed storage 7S protein superfamily. The binding pocket of ABP1 is predominantly hydrophobic with a metal ion deep inside the pocket coordinated by three histidines and a glutamate. Auxin binds within this pocket, with its carboxylate binding the zinc and its aromatic ring binding hydrophobic residues including Trp151. There is a single disulfide between Cys2 and Cys155. No conformational rearrangement of ABP1 was observed when auxin bound to the protein in the crystal, but examination of the structure reveals a possible mechanism of signal transduction.
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===Crystal structure of auxin binding protein===
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Crystal structure of auxin-binding protein 1 in complex with auxin.,Woo EJ, Marshall J, Bauly J, Chen JG, Venis M, Napier RM, Pickersgill RW EMBO J. 2002 Jun 17;21(12):2877-85. PMID:12065401<ref>PMID:12065401</ref>
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{{ABSTRACT_PUBMED_12065401}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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==About this Structure==
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<div class="pdbe-citations 1lr5" style="background-color:#fffaf0;"></div>
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[[1lr5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LR5 OCA].
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== References ==
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<references/>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:012065401</ref><ref group="xtra">PMID:015211523</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Zea mays]]
[[Category: Zea mays]]
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[[Category: Bauley, J.]]
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[[Category: Bauley J]]
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[[Category: Chen, J G.]]
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[[Category: Chen J-G]]
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[[Category: Marshall, J.]]
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[[Category: Marshall J]]
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[[Category: Napier, R M.]]
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[[Category: Napier RM]]
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[[Category: Pickersgill, R W.]]
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[[Category: Pickersgill RW]]
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[[Category: Venis, M.]]
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[[Category: Venis M]]
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[[Category: Woo, E J.]]
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[[Category: Woo EJ]]
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[[Category: Beta jellyroll]]
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[[Category: Double stranded beta helix]]
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[[Category: Germin-like protein]]
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[[Category: Protein binding]]
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Current revision

Crystal structure of auxin binding protein

PDB ID 1lr5

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