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1lw7
From Proteopedia
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| - | [[Image:1lw7.png|left|200px]] | ||
| - | + | ==NADR PROTEIN FROM HAEMOPHILUS INFLUENZAE== | |
| - | + | <StructureSection load='1lw7' size='340' side='right'caption='[[1lw7]], [[Resolution|resolution]] 2.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1lw7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LW7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LW7 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lw7 OCA], [https://pdbe.org/1lw7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lw7 RCSB], [https://www.ebi.ac.uk/pdbsum/1lw7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lw7 ProSAT]</span></td></tr> |
| - | [[1lw7]] is a 1 chain structure with sequence from [ | + | </table> |
| - | + | == Function == | |
| - | == | + | [https://www.uniprot.org/uniprot/NADR_HAEIN NADR_HAEIN] This enzyme has two activities: nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the AMP moiety of ATP to nicotinamide ribonucleotide to form NAD(+).<ref>PMID:12446641</ref> |
| - | < | + | == Evolutionary Conservation == |
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lw/1lw7_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lw7 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Haemophilus influenzae]] | [[Category: Haemophilus influenzae]] | ||
| - | [[Category: Chen | + | [[Category: Large Structures]] |
| - | [[Category: Grishin | + | [[Category: Chen B]] |
| - | [[Category: Kurnasov | + | [[Category: Grishin NV]] |
| - | [[Category: Osterman | + | [[Category: Kurnasov OV]] |
| - | [[Category: Robinson | + | [[Category: Osterman AL]] |
| - | [[Category: Singh | + | [[Category: Robinson H]] |
| - | [[Category: Zhang | + | [[Category: Singh SK]] |
| - | + | [[Category: Zhang H]] | |
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Current revision
NADR PROTEIN FROM HAEMOPHILUS INFLUENZAE
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