1l7a

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[[Image:1l7a.png|left|200px]]
 
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{{STRUCTURE_1l7a| PDB=1l7a | SCENE= }}
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==structural Genomics, crystal structure of Cephalosporin C deacetylase==
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<StructureSection load='1l7a' size='340' side='right'caption='[[1l7a]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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===structural Genomics, crystal structure of Cephalosporin C deacetylase===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1l7a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L7A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L7A FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l7a OCA], [https://pdbe.org/1l7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l7a RCSB], [https://www.ebi.ac.uk/pdbsum/1l7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l7a ProSAT], [https://www.topsan.org/Proteins/MCSG/1l7a TOPSAN]</span></td></tr>
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[[1l7a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L7A OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CAH_BACSU CAH_BACSU] Esterase that removed acetyl groups from a number of O-acetylated small substrates, such as acetylated xylose, short xylooligosaccharides and cephalosporin C. Has no activity towards polymeric acetylated xylan. Cannot cleave amide linkages.<ref>PMID:12842474</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l7/1l7a_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l7a ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Cephalosporin-C deacetylase]]
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[[Category: Large Structures]]
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[[Category: Collert, F.]]
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[[Category: Collert F]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak A]]
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[[Category: Koroleva, O.]]
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[[Category: Koroleva O]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Zhang R]]
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[[Category: Zhang, R.]]
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[[Category: Alpha-beta-alpha sandwich]]
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[[Category: Hydrolase]]
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[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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Current revision

structural Genomics, crystal structure of Cephalosporin C deacetylase

PDB ID 1l7a

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