1lq1

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[[Image:1lq1.png|left|200px]]
 
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{{STRUCTURE_1lq1| PDB=1lq1 | SCENE= }}
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==DNA Complexed Structure of the Key Transcription Factor Initiating Development in Sporulation Bacteria==
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<StructureSection load='1lq1' size='340' side='right'caption='[[1lq1]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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===DNA Complexed Structure of the Key Transcription Factor Initiating Development in Sporulation Bacteria===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1lq1]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LQ1 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12176382}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lq1 OCA], [https://pdbe.org/1lq1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lq1 RCSB], [https://www.ebi.ac.uk/pdbsum/1lq1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lq1 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1lq1]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQ1 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/SP0A_BACSU SP0A_BACSU] May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
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==Reference==
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== Evolutionary Conservation ==
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<ref group="xtra">PMID:012176382</ref><references group="xtra"/>
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lq/1lq1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lq1 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Hoch, J A.]]
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[[Category: Large Structures]]
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[[Category: Hoch JA]]
[[Category: Madhusudan]]
[[Category: Madhusudan]]
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[[Category: Msadek, T.]]
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[[Category: Msadek T]]
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[[Category: Varughese, K I.]]
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[[Category: Varughese KI]]
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[[Category: Zapf, J.]]
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[[Category: Zapf J]]
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[[Category: Zhao, H.]]
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[[Category: Zhao H]]
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[[Category: 0a box]]
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[[Category: Dna complexed structure]]
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[[Category: Spo0a]]
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[[Category: Transcription-dna complex]]
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[[Category: Transcriptional activation and repression]]
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Current revision

DNA Complexed Structure of the Key Transcription Factor Initiating Development in Sporulation Bacteria

PDB ID 1lq1

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