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1n22

From Proteopedia

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[[Image:1n22.png|left|200px]]
 
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{{STRUCTURE_1n22| PDB=1n22 | SCENE= }}
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==(+)-Bornyl Diphosphate Synthase: Complex with Mg, pyrophosphate, and (4R)-7-aza-7,8-dihydrolimonene==
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<StructureSection load='1n22' size='340' side='right'caption='[[1n22]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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===(+)-Bornyl Diphosphate Synthase: Complex with Mg, pyrophosphate, and (4R)-7-aza-7,8-dihydrolimonene===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1n22]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salvia_officinalis Salvia officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N22 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12432096}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7A8:(1R)-DIMETHYL-(4-METHYL-CYCLOHEX-3-ENYL)-AMINE'>7A8</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n22 OCA], [https://pdbe.org/1n22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n22 RCSB], [https://www.ebi.ac.uk/pdbsum/1n22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n22 ProSAT]</span></td></tr>
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[[1n22]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salvia_officinalis Salvia officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N22 OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/BPPS_SALOF BPPS_SALOF] Catalyzes the formation of the (+)-camphor precursor (+)-bornyl diphosphate from geranyl diphosphate. The enzyme also produces significant amounts of (+)-alpha-pinene, (+)-camphene, and (+-)-limonene.<ref>PMID:9614092</ref>
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<ref group="xtra">PMID:012432096</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Category: Bornyl diphosphate synthase]]
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n2/1n22_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n22 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Salvia officinalis]]
[[Category: Salvia officinalis]]
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[[Category: Christianson, D W.]]
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[[Category: Christianson DW]]
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[[Category: Coates, R M.]]
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[[Category: Coates RM]]
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[[Category: Croteau, R B.]]
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[[Category: Croteau RB]]
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[[Category: Urbansky, M.]]
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[[Category: Urbansky M]]
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[[Category: Whittington, D A.]]
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[[Category: Whittington DA]]
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[[Category: Wise, M L.]]
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[[Category: Wise ML]]
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[[Category: Isomerase]]
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[[Category: Terpene synthase fold]]
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Current revision

(+)-Bornyl Diphosphate Synthase: Complex with Mg, pyrophosphate, and (4R)-7-aza-7,8-dihydrolimonene

PDB ID 1n22

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