1km0

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[[Image:1km0.png|left|200px]]
 
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{{STRUCTURE_1km0| PDB=1km0 | SCENE= }}
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==Crystal structure of orotidine monophosphate decarboxylase mutant D70N complexed with 6-azaUMP==
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<StructureSection load='1km0' size='340' side='right'caption='[[1km0]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1km0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KM0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KM0 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UP6:6-AZA+URIDINE+5-MONOPHOSPHATE'>UP6</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1km0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1km0 OCA], [https://pdbe.org/1km0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1km0 RCSB], [https://www.ebi.ac.uk/pdbsum/1km0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1km0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/km/1km0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1km0 ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of orotidine monophosphate decarboxylase mutant D70N complexed with 6-azaUMP===
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==See Also==
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*[[Uridine 5'-monophosphate synthase 3D structures|Uridine 5'-monophosphate synthase 3D structures]]
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{{ABSTRACT_PUBMED_11900543}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[1km0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KM0 OCA].
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==Reference==
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<ref group="xtra">PMID:011900543</ref><references group="xtra"/>
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[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Methanothermobacter thermautotrophicus]]
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[[Category: Orotidine-5'-phosphate decarboxylase]]
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[[Category: Gillon W]]
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[[Category: Gillon, W.]]
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[[Category: Pai EF]]
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[[Category: Pai, E F.]]
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[[Category: Wu N]]
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[[Category: Wu, N.]]
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[[Category: Lyase]]
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[[Category: Tim barrel]]
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Current revision

Crystal structure of orotidine monophosphate decarboxylase mutant D70N complexed with 6-azaUMP

PDB ID 1km0

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