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1l5x

From Proteopedia

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[[Image:1l5x.png|left|200px]]
 
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{{STRUCTURE_1l5x| PDB=1l5x | SCENE= }}
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==The 2.0-Angstrom resolution crystal structure of a survival protein E (SurE) homolog from Pyrobaculum aerophilum==
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<StructureSection load='1l5x' size='340' side='right'caption='[[1l5x]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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===The 2.0-Angstrom resolution crystal structure of a survival protein E (SurE) homolog from Pyrobaculum aerophilum===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1l5x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrobaculum_aerophilum Pyrobaculum aerophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L5X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L5X FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12595266}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l5x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l5x OCA], [https://pdbe.org/1l5x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l5x RCSB], [https://www.ebi.ac.uk/pdbsum/1l5x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l5x ProSAT]</span></td></tr>
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[[1l5x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrobaculum_aerophilum Pyrobaculum aerophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L5X OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/SURE1_PYRAE SURE1_PYRAE] Nucleotidase that shows the greatest phosphatase activity on purine (deoxy)nucleoside 5'-monophosphates, particularly the substrates 5'-GMP, 5'-AMP and 2'-deoxy-5'-AMP.<ref>PMID:12595266</ref>
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<ref group="xtra">PMID:012595266</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l5/1l5x_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l5x ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Pyrobaculum aerophilum]]
[[Category: Pyrobaculum aerophilum]]
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[[Category: Clarke, S G.]]
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[[Category: Clarke SG]]
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[[Category: Eisenberg, D.]]
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[[Category: Eisenberg D]]
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[[Category: Katz, J E.]]
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[[Category: Katz JE]]
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[[Category: Mura, C.]]
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[[Category: Mura C]]
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[[Category: Mixed alpha/beta protein]]
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[[Category: N-terminal rossmann-fold like]]
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[[Category: Novel c-terminal domain with beta-hairpin extension]]
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[[Category: Putative acid phosphatase]]
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[[Category: Structural genomic]]
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[[Category: Unknown function]]
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Current revision

The 2.0-Angstrom resolution crystal structure of a survival protein E (SurE) homolog from Pyrobaculum aerophilum

PDB ID 1l5x

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