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1lk9

From Proteopedia

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[[Image:1lk9.png|left|200px]]
 
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{{STRUCTURE_1lk9| PDB=1lk9 | SCENE= }}
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==The Three-dimensional Structure of Alliinase from Garlic==
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<StructureSection load='1lk9' size='340' side='right'caption='[[1lk9]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
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===The Three-dimensional Structure of Alliinase from Garlic===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1lk9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Allium_sativum Allium sativum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LK9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LK9 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12235163}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DHA:2-AMINO-ACRYLIC+ACID'>DHA</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lk9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lk9 OCA], [https://pdbe.org/1lk9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lk9 RCSB], [https://www.ebi.ac.uk/pdbsum/1lk9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lk9 ProSAT]</span></td></tr>
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[[1lk9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Allium_sativum Allium sativum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LK9 OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/ALLN1_ALLSA ALLN1_ALLSA] Able to cleave the C-S bond of sulfoxide derivatives of Cys to produce allicin, thus giving rise to all sulfur compounds which are responsible for most of the properties of garlic, such as the specific smell and flavor as well as the health benefits like blood lipid or blood pressure lowering.
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<ref group="xtra">PMID:012235163</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Category: Alliin lyase]]
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lk/1lk9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lk9 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Allium sativum]]
[[Category: Allium sativum]]
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[[Category: Hilgenfeld, R.]]
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[[Category: Large Structures]]
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[[Category: Kuettner, E B.]]
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[[Category: Hilgenfeld R]]
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[[Category: Weiss, M S.]]
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[[Category: Kuettner EB]]
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[[Category: Chloride binding]]
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[[Category: Weiss MS]]
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[[Category: Egf-like domain]]
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[[Category: Lyase]]
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[[Category: Plp type 1]]
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Current revision

The Three-dimensional Structure of Alliinase from Garlic

PDB ID 1lk9

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