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1mum

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[[Image:1mum.png|left|200px]]
 
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{{STRUCTURE_1mum| PDB=1mum | SCENE= }}
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==Structure of the 2-Methylisocitrate Lyase (PrpB) from Escherichia coli==
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<StructureSection load='1mum' size='340' side='right'caption='[[1mum]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===Structure of the 2-Methylisocitrate Lyase (PrpB) from Escherichia coli===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1mum]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MUM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MUM FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12706720}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mum OCA], [https://pdbe.org/1mum PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mum RCSB], [https://www.ebi.ac.uk/pdbsum/1mum PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mum ProSAT]</span></td></tr>
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[[1mum]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MUM OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/PRPB_ECOLI PRPB_ECOLI] Catalyzes the formation of pyruvate and succinate from 2-methylisocitrate.<ref>PMID:11422389</ref> <ref>PMID:15723538</ref>
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<ref group="xtra">PMID:012706720</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mu/1mum_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mum ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Methylisocitrate lyase]]
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[[Category: Large Structures]]
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[[Category: Grimm, C.]]
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[[Category: Grimm C]]
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[[Category: Reuter, K.]]
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[[Category: Reuter K]]
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[[Category: Lyase]]
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[[Category: Methylcitrate cycle]]
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[[Category: Methylisocitrate]]
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[[Category: Prpb]]
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[[Category: Tim-barrel]]
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Current revision

Structure of the 2-Methylisocitrate Lyase (PrpB) from Escherichia coli

PDB ID 1mum

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