1lv0
From Proteopedia
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- | [[Image:1lv0.png|left|200px]] | ||
- | + | ==Crystal structure of the Rab effector guanine nucleotide dissociation inhibitor (GDI) in complex with a geranylgeranyl (GG) peptide== | |
+ | <StructureSection load='1lv0' size='340' side='right'caption='[[1lv0]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[1lv0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LV0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LV0 FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GER:GERAN-8-YL+GERAN'>GER</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lv0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lv0 OCA], [https://pdbe.org/1lv0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lv0 RCSB], [https://www.ebi.ac.uk/pdbsum/1lv0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lv0 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/GDIA_BOVIN GDIA_BOVIN] Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lv/1lv0_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lv0 ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
- | == | + | ==See Also== |
- | + | *[[Guanine nucleotide dissociation inhibitor|Guanine nucleotide dissociation inhibitor]] | |
- | + | __TOC__ | |
- | + | </StructureSection> | |
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- | [[ | + | |
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- | < | + | |
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
- | [[Category: Alory | + | [[Category: Large Structures]] |
- | [[Category: An | + | [[Category: Alory C]] |
- | [[Category: Balch | + | [[Category: An Y]] |
- | [[Category: Chen | + | [[Category: Balch WE]] |
- | [[Category: Gibbs | + | [[Category: Chen W]] |
- | [[Category: Matteson | + | [[Category: Gibbs RA]] |
- | [[Category: Sakisaka | + | [[Category: Matteson J]] |
- | [[Category: Shao | + | [[Category: Sakisaka T]] |
- | [[Category: Wilson | + | [[Category: Shao Y]] |
- | + | [[Category: Wilson IA]] | |
- | + |
Current revision
Crystal structure of the Rab effector guanine nucleotide dissociation inhibitor (GDI) in complex with a geranylgeranyl (GG) peptide
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Categories: Bos taurus | Large Structures | Alory C | An Y | Balch WE | Chen W | Gibbs RA | Matteson J | Sakisaka T | Shao Y | Wilson IA