1m11

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[[Image:1m11.png|left|200px]]
 
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{{STRUCTURE_1m11| PDB=1m11 | SCENE= }}
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==structural model of human decay-accelerating factor bound to echovirus 7 from cryo-electron microscopy==
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<SX load='1m11' size='340' side='right' viewer='molstar' caption='[[1m11]], [[Resolution|resolution]] 16.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1m11]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Echovirus_E7 Echovirus E7] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M11 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M11 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 16&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m11 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m11 OCA], [https://pdbe.org/1m11 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m11 RCSB], [https://www.ebi.ac.uk/pdbsum/1m11 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m11 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m1/1m11_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m11 ConSurf].
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<div style="clear:both"></div>
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===structural model of human decay-accelerating factor bound to echovirus 7 from cryo-electron microscopy===
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==See Also==
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*[[CD55|CD55]]
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{{ABSTRACT_PUBMED_12119400}}
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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[[1m11]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Echovirus_e7 Echovirus e7] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M11 OCA].
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__TOC__
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</SX>
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==Reference==
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[[Category: Echovirus E7]]
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<ref group="xtra">PMID:012119400</ref><references group="xtra"/>
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[[Category: Echovirus e7]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Baker, T S.]]
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[[Category: Large Structures]]
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[[Category: Bator, C M.]]
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[[Category: Baker TS]]
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[[Category: Chipman, P R.]]
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[[Category: Bator CM]]
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[[Category: He, Y.]]
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[[Category: Chipman PR]]
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[[Category: Kuhn, R J.]]
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[[Category: He Y]]
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[[Category: Lin, F.]]
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[[Category: Kuhn RJ]]
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[[Category: Medof, M E.]]
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[[Category: Lin F]]
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[[Category: Rossmann, M G.]]
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[[Category: Medof ME]]
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[[Category: Shoham, M.]]
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[[Category: Rossmann MG]]
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[[Category: Decay-accelerating factor]]
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[[Category: Shoham M]]
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[[Category: Icosahedral virus]]
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[[Category: Scr]]
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[[Category: Virus-receptor complex]]
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Current revision

structural model of human decay-accelerating factor bound to echovirus 7 from cryo-electron microscopy

1m11, resolution 16.00Å

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