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1lts

From Proteopedia

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[[Image:1lts.png|left|200px]]
 
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{{STRUCTURE_1lts| PDB=1lts | SCENE= }}
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==REFINED STRUCTURE OF E. COLI HEAT LABILE ENTEROTOXIN, A CLOSE RELATIVE OF CHOLERA TOXIN==
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<StructureSection load='1lts' size='340' side='right'caption='[[1lts]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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===REFINED STRUCTURE OF E. COLI HEAT LABILE ENTEROTOXIN, A CLOSE RELATIVE OF CHOLERA TOXIN===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1lts]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LTS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LTS FirstGlance]. <br>
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{{ABSTRACT_PUBMED_8478941}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lts FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lts OCA], [https://pdbe.org/1lts PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lts RCSB], [https://www.ebi.ac.uk/pdbsum/1lts PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lts ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1lts]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LTS OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/ELBP_ECOLX ELBP_ECOLX] The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase.
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==Reference==
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== Evolutionary Conservation ==
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<ref group="xtra">PMID:008478941</ref><ref group="xtra">PMID:011170211</ref><references group="xtra"/>
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lt/1lts_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lts ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Hol, W G.J.]]
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[[Category: Large Structures]]
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[[Category: Sixma, T K.]]
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[[Category: Hol WGJ]]
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[[Category: Toxin]]
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[[Category: Sixma TK]]

Current revision

REFINED STRUCTURE OF E. COLI HEAT LABILE ENTEROTOXIN, A CLOSE RELATIVE OF CHOLERA TOXIN

PDB ID 1lts

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