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1mij
From Proteopedia
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| - | [[Image:1mij.png|left|200px]] | ||
| - | + | ==Crystal Structure of the Homeo-prospero Domain of D. melanogaster Prospero== | |
| - | + | <StructureSection load='1mij' size='340' side='right'caption='[[1mij]], [[Resolution|resolution]] 2.05Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1mij]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MIJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mij FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mij OCA], [https://pdbe.org/1mij PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mij RCSB], [https://www.ebi.ac.uk/pdbsum/1mij PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mij ProSAT]</span></td></tr> |
| - | [[1mij]] is a 1 chain structure with sequence from [ | + | </table> |
| - | + | == Function == | |
| - | == | + | [https://www.uniprot.org/uniprot/PROS_DROME PROS_DROME] Required for proper neuronal differentiation of most or all neurons and their precursors in central and peripheral nervous systems, axonal outgrowth and pathfinding. Not required for the specification of neuronal identity. May regulate transcription by binding to DNA.<ref>PMID:1720353</ref> <ref>PMID:1842358</ref> <ref>PMID:1540176</ref> <ref>PMID:11051550</ref> |
| - | < | + | == Evolutionary Conservation == |
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mi/1mij_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mij ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Doe CQ]] |
| - | [[Category: | + | [[Category: Matthews BW]] |
| - | [[Category: | + | [[Category: Ryter JM]] |
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Current revision
Crystal Structure of the Homeo-prospero Domain of D. melanogaster Prospero
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