This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1m8a

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1m8a" [edit=sysop:move=sysop])
Current revision (08:32, 10 April 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1m8a.png|left|200px]]
 
-
{{STRUCTURE_1m8a| PDB=1m8a | SCENE= }}
+
==Human MIP-3alpha/CCL20==
-
 
+
<StructureSection load='1m8a' size='340' side='right'caption='[[1m8a]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
-
===Human MIP-3alpha/CCL20===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1m8a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M8A FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_12149255}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m8a OCA], [https://pdbe.org/1m8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m8a RCSB], [https://www.ebi.ac.uk/pdbsum/1m8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m8a ProSAT]</span></td></tr>
-
[[1m8a]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M8A OCA].
+
</table>
-
 
+
== Function ==
-
==Reference==
+
[https://www.uniprot.org/uniprot/CCL20_HUMAN CCL20_HUMAN] Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213.<ref>PMID:12149255</ref>
-
<ref group="xtra">PMID:012149255</ref><references group="xtra"/>
+
== Evolutionary Conservation ==
-
[[Category: Boulegue, C.]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Hoover, D M.]]
+
Check<jmol>
-
[[Category: Lu, W.]]
+
<jmolCheckbox>
-
[[Category: Lubkowski, J.]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m8/1m8a_consurf.spt"</scriptWhenChecked>
-
[[Category: Oppenheim, J J.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Tucker, K.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Yang, D.]]
+
</jmolCheckbox>
-
[[Category: Cc-chemokine]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m8a ConSurf].
-
[[Category: Cytokine]]
+
<div style="clear:both"></div>
-
[[Category: Il-8 type dimer]]
+
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Boulegue C]]
 +
[[Category: Hoover DM]]
 +
[[Category: Lu W]]
 +
[[Category: Lubkowski J]]
 +
[[Category: Oppenheim JJ]]
 +
[[Category: Tucker K]]
 +
[[Category: Yang D]]

Current revision

Human MIP-3alpha/CCL20

PDB ID 1m8a

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1m8a"
Personal tools