1n66

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1n66" [edit=sysop:move=sysop])
Current revision (18:52, 29 November 2023) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1n66.png|left|200px]]
 
-
{{STRUCTURE_1n66| PDB=1n66 | SCENE= }}
+
==Structure of the pyrimidine-rich internal loop in the Y-domain of poliovirus 3'UTR==
 +
<StructureSection load='1n66' size='340' side='right'caption='[[1n66]]' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[1n66]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N66 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N66 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n66 OCA], [https://pdbe.org/1n66 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n66 RCSB], [https://www.ebi.ac.uk/pdbsum/1n66 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n66 ProSAT]</span></td></tr>
 +
</table>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Formation of non-canonical base-pairs in RNA often plays a very important functional role. In addition they frequently serve as factors in stabilizing the secondary structure elements that provide the frame of large compact RNA structures. Here we describe the structure of an internal loop containing a 5'CU3'/5'UU3' non-canonical tandem base-pair motif, which is conserved within the 3'-UTR of poliovirus-like enteroviruses. Structural details reveal striking regularities of the local helix geometry, resulting from alternating geometrical adjustments, which are important for understanding and predicting stabilities and configurations of tandem non-canonical base-pairs. The C-U and U-U base-pairs severely contract the minor groove of the sugar-phosphate backbone, which might be important for protein recognition or binding to other RNA elements.
-
===Structure of the pyrimidine-rich internal loop in the Y-domain of poliovirus 3'UTR===
+
Structure of the pyrimidine-rich internal loop in the poliovirus 3'-UTR: the importance of maintaining pseudo-2-fold symmetry in RNA helices containing two adjacent non-canonical base-pairs.,Lescrinier EM, Tessari M, van Kuppeveld FJ, Melchers WJ, Hilbers CW, Heus HA J Mol Biol. 2003 Aug 22;331(4):759-69. PMID:12909008<ref>PMID:12909008</ref>
-
{{ABSTRACT_PUBMED_12909008}}
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
 
+
</div>
-
==About this Structure==
+
<div class="pdbe-citations 1n66" style="background-color:#fffaf0;"></div>
-
[[1n66]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N66 OCA].
+
== References ==
-
[[Category: Heus, H A.]]
+
<references/>
-
[[Category: Hilbers, C W.]]
+
__TOC__
-
[[Category: Kuppeveld, F J.van.]]
+
</StructureSection>
-
[[Category: Lescrinier, E M.]]
+
[[Category: Large Structures]]
-
[[Category: Melchers, W J.]]
+
[[Category: Heus HA]]
-
[[Category: Tessari, M.]]
+
[[Category: Hilbers CW]]
-
[[Category: Rna]]
+
[[Category: Lescrinier EM]]
-
[[Category: Rna internal loop]]
+
[[Category: Melchers WJ]]
 +
[[Category: Tessari M]]
 +
[[Category: Van Kuppeveld FJ]]

Current revision

Structure of the pyrimidine-rich internal loop in the Y-domain of poliovirus 3'UTR

PDB ID 1n66

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1n66"
Personal tools