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1nu3

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[[Image:1nu3.png|left|200px]]
 
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{{STRUCTURE_1nu3| PDB=1nu3 | SCENE= }}
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==Limonene-1,2-epoxide hydrolase in complex with valpromide==
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<StructureSection load='1nu3' size='340' side='right'caption='[[1nu3]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1nu3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NU3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NU3 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=VPR:2-PROPYLPENTANAMIDE'>VPR</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nu3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nu3 OCA], [https://pdbe.org/1nu3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nu3 RCSB], [https://www.ebi.ac.uk/pdbsum/1nu3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nu3 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LIMA_RHOER LIMA_RHOER] Catalyzes the conversion of limonene-1,2-epoxide to limonene-1,2-diol. Can use both the (-) and (+) isomers of limonene-1,2-epoxide as substrates and also has some activity with 1-methylcyclohexene oxide, cyclohexene oxide and indene oxide as substrates.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nu/1nu3_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nu3 ConSurf].
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<div style="clear:both"></div>
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===Limonene-1,2-epoxide hydrolase in complex with valpromide===
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==See Also==
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*[[Epoxide hydrolase 3D structures|Epoxide hydrolase 3D structures]]
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{{ABSTRACT_PUBMED_12773375}}
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*[[Limonene-1%2C2-epoxide hydrolase|Limonene-1%2C2-epoxide hydrolase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[1nu3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NU3 OCA].
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[[Category: Large Structures]]
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==Reference==
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<ref group="xtra">PMID:012773375</ref><references group="xtra"/>
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[[Category: Limonene-1,2-epoxide hydrolase]]
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[[Category: Rhodococcus erythropolis]]
[[Category: Rhodococcus erythropolis]]
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[[Category: Arand, M.]]
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[[Category: Arand M]]
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[[Category: Bergfors, T.]]
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[[Category: Bergfors T]]
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[[Category: Bont, J A.M de.]]
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[[Category: Hallberg BM]]
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[[Category: Hallberg, B M.]]
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[[Category: Jones TA]]
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[[Category: Jones, T A.]]
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[[Category: Mowbray SL]]
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[[Category: Mowbray, S L.]]
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[[Category: Oesch F]]
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[[Category: Oesch, F.]]
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[[Category: Zou J]]
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[[Category: Werf, M J.van der.]]
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[[Category: De Bont JAM]]
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[[Category: Zou, J.]]
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[[Category: Van der Werf MJ]]
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[[Category: Hydrolase]]
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[[Category: Protein-ligand complex]]
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Current revision

Limonene-1,2-epoxide hydrolase in complex with valpromide

PDB ID 1nu3

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