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1ka0

From Proteopedia

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[[Image:1ka0.png|left|200px]]
 
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{{STRUCTURE_1ka0| PDB=1ka0 | SCENE= }}
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==The PAPase Hal2p complexed with a sodium ion and the reaction product AMP==
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<StructureSection load='1ka0' size='340' side='right'caption='[[1ka0]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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===The PAPase Hal2p complexed with a sodium ion and the reaction product AMP===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ka0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KA0 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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[[1ka0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KA0 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ka0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ka0 OCA], [https://pdbe.org/1ka0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ka0 RCSB], [https://www.ebi.ac.uk/pdbsum/1ka0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ka0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MET22_YEAST MET22_YEAST] Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Regulates the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS. Involved in salt tolerance. Confers resistance to lithium.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ka/1ka0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ka0 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Albert, A.]]
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[[Category: Albert A]]
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[[Category: Blundell, T L.]]
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[[Category: Blundell TL]]
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[[Category: Patel, S.]]
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[[Category: Patel S]]
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[[Category: Hydrolase]]
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[[Category: Inositol]]
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[[Category: Nucleotidase]]
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[[Category: Salt tolerance]]
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Current revision

The PAPase Hal2p complexed with a sodium ion and the reaction product AMP

PDB ID 1ka0

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