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1l6p

From Proteopedia

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[[Image:1l6p.png|left|200px]]
 
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{{STRUCTURE_1l6p| PDB=1l6p | SCENE= }}
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==N-terminal of DsbD (residues 20-144) from E. coli.==
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<StructureSection load='1l6p' size='340' side='right'caption='[[1l6p]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1l6p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L6P FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l6p OCA], [https://pdbe.org/1l6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l6p RCSB], [https://www.ebi.ac.uk/pdbsum/1l6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l6p ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DSBD_ECOLI DSBD_ECOLI] Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm, thereby maintaining the active site of DsbC, DsbE and DsbG in a reduced state. This transfer involves a cascade of disulfide bond formation and reduction steps.[HAMAP-Rule:MF_00399]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l6/1l6p_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l6p ConSurf].
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<div style="clear:both"></div>
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===N-terminal of DsbD (residues 20-144) from E. coli.===
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==See Also==
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*[[Thiol:disulfide interchange protein 3D structures|Thiol:disulfide interchange protein 3D structures]]
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{{ABSTRACT_PUBMED_12033924}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[1l6p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L6P OCA].
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==Reference==
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<ref group="xtra">PMID:012033924</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Goulding, C W.]]
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[[Category: Large Structures]]
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[[Category: Parseghian, A.]]
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[[Category: Goulding CW]]
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[[Category: Sawaya, M R.]]
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[[Category: Parseghian A]]
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[[Category: Disulfide bond isomerase protein]]
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[[Category: Sawaya MR]]
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[[Category: Electron transport]]
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[[Category: Immunoglobulin-like fold]]
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Current revision

N-terminal of DsbD (residues 20-144) from E. coli.

PDB ID 1l6p

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