1nyc
From Proteopedia
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| - | [[Image:1nyc.png|left|200px]] | ||
| - | + | ==Staphostatins resemble lipocalins, not cystatins in fold.== | |
| - | + | <StructureSection load='1nyc' size='340' side='right'caption='[[1nyc]], [[Resolution|resolution]] 1.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1nyc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MW2 Staphylococcus aureus subsp. aureus MW2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NYC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NYC FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nyc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nyc OCA], [https://pdbe.org/1nyc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nyc RCSB], [https://www.ebi.ac.uk/pdbsum/1nyc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nyc ProSAT]</span></td></tr> |
| - | [[1nyc]] is a 2 chain structure with sequence from [ | + | </table> |
| - | [ | + | == Function == |
| - | [[ | + | [https://www.uniprot.org/uniprot/SSPC_STAAW SSPC_STAAW] Specifically inhibits the cysteine protease staphopain B (SspB) by blocking the active site of the enzyme. Probably required to protect cytoplasmic proteins from being degraded by prematurely activated/folded prostaphopain B. Also involved in growth capacity, viability and bacterial morphology (By similarity). |
| - | [[ | + | __TOC__ |
| - | [[ | + | </StructureSection> |
| - | [ | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Staphylococcus aureus subsp. aureus MW2]] |
| - | [[Category: | + | [[Category: Bochtler M]] |
| - | [[Category: | + | [[Category: Dubin A]] |
| - | [[Category: | + | [[Category: Filipek R]] |
| - | [[Category: | + | [[Category: Kosowska K]] |
| - | [[Category: | + | [[Category: Potempa J]] |
| - | [[Category: | + | [[Category: Rzychon M]] |
| + | [[Category: Sabat A]] | ||
Current revision
Staphostatins resemble lipocalins, not cystatins in fold.
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