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4f2u
From Proteopedia
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| - | [[Image:4f2u.jpg|left|200px]] | ||
| - | + | ==Structure of the N254Y/H258Y double mutant of the Phosphatidylinositol-Specific Phospholipase C from S.aureus== | |
| + | <StructureSection load='4f2u' size='340' side='right'caption='[[4f2u]], [[Resolution|resolution]] 2.19Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4f2u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_str._Newman Staphylococcus aureus subsp. aureus str. Newman]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F2U FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.19Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f2u OCA], [https://pdbe.org/4f2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f2u RCSB], [https://www.ebi.ac.uk/pdbsum/4f2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f2u ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PLC_STAAE PLC_STAAE] Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Potential virulence factor. | ||
| - | == | + | ==See Also== |
| - | + | *[[Phospholipase C|Phospholipase C]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| - | [[ | + | [[Category: Staphylococcus aureus subsp. aureus str. Newman]] |
| - | [[Category: | + | [[Category: Cheng J]] |
| - | [[Category: Staphylococcus aureus subsp. aureus str. | + | [[Category: Gershenson A]] |
| - | [[Category: Cheng | + | [[Category: Goldstein R]] |
| - | [[Category: Gershenson | + | [[Category: Roberts MF]] |
| - | [[Category: Goldstein | + | [[Category: Stec B]] |
| - | [[Category: Roberts | + | |
| - | [[Category: Stec | + | |
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Current revision
Structure of the N254Y/H258Y double mutant of the Phosphatidylinositol-Specific Phospholipase C from S.aureus
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