4a46

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[[Image:4a46.jpg|left|200px]]
 
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{{STRUCTURE_4a46| PDB=4a46 | SCENE= }}
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==Crosstalk between Cu(I) and Zn(II) homeostasis==
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<StructureSection load='4a46' size='340' side='right'caption='[[4a46]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4a46]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Synechocystis_sp._PCC_6803 Synechocystis sp. PCC 6803]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A46 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A46 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a46 OCA], [https://pdbe.org/4a46 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a46 RCSB], [https://www.ebi.ac.uk/pdbsum/4a46 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a46 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/P73213_SYNY3 P73213_SYNY3]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The copper metallochaperone Atx1 and the N-terminal metal-binding domain of a copper-transporting ATP-ase can form tight Zn(II)-mediated hetero-complexes in both cyanobacteria and humans. Copper and zinc homeostasis could be linked by metal binding to these CXXC-containing proteins.
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===Crosstalk between Cu(I) and Zn(II) homeostasis===
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Crosstalk between Cu(I) and Zn(II) homeostasis via Atx1 and cognate domains.,Badarau A, Basle A, Firbank SJ, Dennison C Chem Commun (Camb). 2013 Sep 21;49(73):8000-2. doi: 10.1039/c3cc42709a. Epub 2013, Aug 7. PMID:23926594<ref>PMID:23926594</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==About this Structure==
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</div>
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[[4a46]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Synechocystis_sp._pcc_6803 Synechocystis sp. pcc 6803]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A46 OCA].
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<div class="pdbe-citations 4a46" style="background-color:#fffaf0;"></div>
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[[Category: Synechocystis sp. pcc 6803]]
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== References ==
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[[Category: Badarau, A.]]
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<references/>
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[[Category: Basle, A.]]
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__TOC__
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[[Category: Denninson, C.]]
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</StructureSection>
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[[Category: Firbank, S J.]]
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[[Category: Large Structures]]
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[[Category: Copper homeostasis]]
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[[Category: Synechocystis sp. PCC 6803]]
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[[Category: Metal-transporting atpase]]
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[[Category: Badarau A]]
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[[Category: Transport protein]]
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[[Category: Basle A]]
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[[Category: Zinc homeostasis]]
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[[Category: Denninson C]]
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[[Category: Firbank SJ]]

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Crosstalk between Cu(I) and Zn(II) homeostasis

PDB ID 4a46

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