1scz

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[[Image:1scz.gif|left|200px]]<br /><applet load="1scz" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1scz, resolution 2.20&Aring;" />
 
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'''Improved structural model for the catalytic domain of E.coli dihydrolipoamide succinyltransferase'''<br />
 
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==About this Structure==
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==Improved structural model for the catalytic domain of E.coli dihydrolipoamide succinyltransferase==
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1SCZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Active as [http://en.wikipedia.org/wiki/Dihydrolipoyllysine-residue_succinyltransferase Dihydrolipoyllysine-residue succinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.61 2.3.1.61] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SCZ OCA].
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<StructureSection load='1scz' size='340' side='right'caption='[[1scz]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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[[Category: Dihydrolipoyllysine-residue succinyltransferase]]
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== Structural highlights ==
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[[Category: Escherichia coli]]
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<table><tr><td colspan='2'>[[1scz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SCZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SCZ FirstGlance]. <br>
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[[Category: Single protein]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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[[Category: Arabashi, A.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1scz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1scz OCA], [https://pdbe.org/1scz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1scz RCSB], [https://www.ebi.ac.uk/pdbsum/1scz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1scz ProSAT]</span></td></tr>
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[[Category: Bunzel, B.]]
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</table>
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[[Category: Carson, M.]]
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== Function ==
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[[Category: DeLucas, L.]]
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[https://www.uniprot.org/uniprot/ODO2_ECOLI ODO2_ECOLI] The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
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[[Category: Gray, R.]]
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== Evolutionary Conservation ==
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[[Category: Huang, W Y.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Johnson, D.]]
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Check<jmol>
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[[Category: Li, S.]]
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<jmolCheckbox>
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[[Category: Lin, G.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sc/1scz_consurf.spt"</scriptWhenChecked>
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[[Category: Lu, S.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Luan, C H.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Luo, D.]]
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</jmolCheckbox>
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[[Category: Luo, M.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1scz ConSurf].
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[[Category: Nagy, L.]]
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<div style="clear:both"></div>
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[[Category: Pruett, P.]]
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[[Category: Qiu, S.]]
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[[Category: Schormann, N.]]
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[[Category: Symersky, J.]]
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[[Category: Tsao, J.]]
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[[Category: Zhang, Z.]]
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[[Category: alpha and beta (2 layers)]]
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[[Category: cat-like]]
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[[Category: coa-dependent acyltransferase]]
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[[Category: mixed beta-sheeet of 6 strands]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:00:12 2008''
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==See Also==
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*[[2-oxoglutarate dehydrogenase 3D structures|2-oxoglutarate dehydrogenase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Arabashi A]]
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[[Category: Bunzel B]]
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[[Category: Carson M]]
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[[Category: DeLucas L]]
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[[Category: Gray R]]
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[[Category: Huang W-Y]]
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[[Category: Johnson D]]
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[[Category: Li S]]
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[[Category: Lin G]]
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[[Category: Lu S]]
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[[Category: Luan C-H]]
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[[Category: Luo D]]
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[[Category: Luo M]]
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[[Category: Nagy L]]
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[[Category: Pruett P]]
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[[Category: Qiu S]]
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[[Category: Schormann N]]
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[[Category: Symersky J]]
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[[Category: Tsao J]]
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[[Category: Zhang Z]]

Current revision

Improved structural model for the catalytic domain of E.coli dihydrolipoamide succinyltransferase

PDB ID 1scz

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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