1oaa

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m (Protected "1oaa" [edit=sysop:move=sysop])
Current revision (08:01, 14 February 2024) (edit) (undo)
 
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[[Image:1oaa.png|left|200px]]
 
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{{STRUCTURE_1oaa| PDB=1oaa | SCENE= }}
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==MOUSE SEPIAPTERIN REDUCTASE COMPLEXED WITH NADP AND OXALOACETATE==
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<StructureSection load='1oaa' size='340' side='right'caption='[[1oaa]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
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===MOUSE SEPIAPTERIN REDUCTASE COMPLEXED WITH NADP AND OXALOACETATE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1oaa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OAA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OAA FirstGlance]. <br>
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{{ABSTRACT_PUBMED_9405351}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=OAA:OXALOACETATE+ION'>OAA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oaa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oaa OCA], [https://pdbe.org/1oaa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oaa RCSB], [https://www.ebi.ac.uk/pdbsum/1oaa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oaa ProSAT]</span></td></tr>
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[[1oaa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OAA OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/SPRE_MOUSE SPRE_MOUSE] Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
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<ref group="xtra">PMID:009405351</ref><ref group="xtra">PMID:011917145</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oa/1oaa_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oaa ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Sepiapterin reductase]]
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[[Category: Auerbach G]]
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[[Category: Auerbach, G.]]
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[[Category: Bacher A]]
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[[Category: Bacher, A.]]
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[[Category: Herrmann A]]
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[[Category: Herrmann, A.]]
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[[Category: Huber R]]
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[[Category: Huber, R.]]
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[[Category: Oxidoreductase]]
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[[Category: Sepiapterin reductase]]
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[[Category: Tetrahydrobiopterin]]
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Current revision

MOUSE SEPIAPTERIN REDUCTASE COMPLEXED WITH NADP AND OXALOACETATE

PDB ID 1oaa

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