1or7

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[[Image:1or7.png|left|200px]]
 
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{{STRUCTURE_1or7| PDB=1or7 | SCENE= }}
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==Crystal Structure of Escherichia coli sigmaE with the Cytoplasmic Domain of its Anti-sigma RseA==
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<StructureSection load='1or7' size='340' side='right'caption='[[1or7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1or7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OR7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OR7 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1or7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1or7 OCA], [https://pdbe.org/1or7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1or7 RCSB], [https://www.ebi.ac.uk/pdbsum/1or7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1or7 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RPOE_ECOLI RPOE_ECOLI] Sigma factors are initiation factors that promote the attachment of RNA polymerase (RNAP) to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma-E controls the envelope stress response, responding to periplasmic protein stress, increased levels of periplasmic lipopolysaccharide (LPS) as well as heat shock and oxidative stress; it controls protein processing in the extracytoplasmic compartment. The 90 member regulon consists of the genes necessary for the synthesis and maintenance of both proteins and LPS of the outer membrane.<ref>PMID:7889935</ref> <ref>PMID:7889934</ref> <ref>PMID:2691330</ref> <ref>PMID:9159522</ref> <ref>PMID:9159523</ref> <ref>PMID:16336047</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/or/1or7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1or7 ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of Escherichia coli sigmaE with the Cytoplasmic Domain of its Anti-sigma RseA===
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==See Also==
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*[[Sigma factor 3D structures|Sigma factor 3D structures]]
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{{ABSTRACT_PUBMED_12718891}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1or7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OR7 OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:012718891</ref><ref group="xtra">PMID:015213388</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Campbell, E A.]]
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[[Category: Large Structures]]
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[[Category: Darst, S A.]]
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[[Category: Campbell EA]]
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[[Category: Gross, C A.]]
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[[Category: Darst SA]]
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[[Category: Gruber, T M.]]
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[[Category: Gross CA]]
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[[Category: Sharp, M M.]]
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[[Category: Gruber TM]]
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[[Category: Tupy, J L.]]
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[[Category: Sharp MM]]
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[[Category: Wang, S.]]
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[[Category: Tupy JL]]
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[[Category: Dna-binding]]
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[[Category: Wang S]]
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[[Category: Regulation]]
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[[Category: Transcription]]
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[[Category: Transmembrane]]
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Current revision

Crystal Structure of Escherichia coli sigmaE with the Cytoplasmic Domain of its Anti-sigma RseA

PDB ID 1or7

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