1op1
From Proteopedia
(Difference between revisions)
| (9 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:1op1.png|left|200px]] | ||
| - | + | ==Solution NMR structure of domain 1 of receptor associated protein== | |
| - | + | <StructureSection load='1op1' size='340' side='right'caption='[[1op1]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1op1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OP1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OP1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1op1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1op1 OCA], [https://pdbe.org/1op1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1op1 RCSB], [https://www.ebi.ac.uk/pdbsum/1op1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1op1 ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1op1]] is a 1 chain structure with sequence from [ | + | == Disease == |
| - | + | [https://www.uniprot.org/uniprot/AMRP_HUMAN AMRP_HUMAN] Note=In complex with the alpha-2-MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis. | |
| - | == | + | == Function == |
| - | < | + | [https://www.uniprot.org/uniprot/AMRP_HUMAN AMRP_HUMAN] Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330. |
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/op/1op1_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1op1 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Migliorini | + | [[Category: Large Structures]] |
| - | [[Category: Strickland | + | [[Category: Migliorini M]] |
| - | [[Category: Wang | + | [[Category: Strickland DK]] |
| - | [[Category: Wu | + | [[Category: Wang Y-X]] |
| - | [[Category: Yu | + | [[Category: Wu Y]] |
| - | + | [[Category: Yu P]] | |
| - | + | ||
Current revision
Solution NMR structure of domain 1 of receptor associated protein
| |||||||||||
Categories: Homo sapiens | Large Structures | Migliorini M | Strickland DK | Wang Y-X | Wu Y | Yu P
