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1of9
From Proteopedia
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| - | [[Image:1of9.png|left|200px]] | ||
| - | + | ==Solution structure of the pore forming toxin of entamoeba histolytica (Amoebapore A)== | |
| - | + | <StructureSection load='1of9' size='340' side='right'caption='[[1of9]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1of9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Entamoeba_histolytica Entamoeba histolytica]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OF9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OF9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1of9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1of9 OCA], [https://pdbe.org/1of9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1of9 RCSB], [https://www.ebi.ac.uk/pdbsum/1of9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1of9 ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1of9]] is a 1 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/PFPA_ENTHI PFPA_ENTHI] Forms pores in the cytoplasmic membrane of host cells. Has antibacterial activity against M.luteus, no activity against E.coli. Implicated in the cytolytic activity of the parasite. | |
| - | == | + | == Evolutionary Conservation == |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/of/1of9_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1of9 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Entamoeba histolytica]] | [[Category: Entamoeba histolytica]] | ||
| - | [[Category: Bruhn | + | [[Category: Large Structures]] |
| - | [[Category: Dingley | + | [[Category: Bruhn H]] |
| - | [[Category: Grotzinger | + | [[Category: Dingley AJ]] |
| - | [[Category: Hecht | + | [[Category: Grotzinger J]] |
| - | [[Category: Leippe | + | [[Category: Hecht O]] |
| - | + | [[Category: Leippe M]] | |
| - | [[Category: Schleinkofer | + | [[Category: Schleinkofer K]] |
| - | [[Category: | + | [[Category: Van Nuland N]] |
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Current revision
Solution structure of the pore forming toxin of entamoeba histolytica (Amoebapore A)
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