4enh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:05, 14 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:4enh.png|left|200px]]
 
-
{{STRUCTURE_4enh| PDB=4enh | SCENE= }}
+
==Crystal Structure of Human Cytochrome P450 CYP46A1 with Fluvoxamine Bound==
-
 
+
<StructureSection load='4enh' size='340' side='right'caption='[[4enh]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-
===Crystal Structure of Human Cytochrome P450 CYP46A1 with Fluvoxamine Bound===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[4enh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ENH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ENH FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_22859721}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FVX:FLUVOXAMINE'>FVX</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4enh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4enh OCA], [https://pdbe.org/4enh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4enh RCSB], [https://www.ebi.ac.uk/pdbsum/4enh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4enh ProSAT]</span></td></tr>
-
[[4enh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ENH OCA].
+
</table>
-
 
+
== Function ==
-
==Reference==
+
[https://www.uniprot.org/uniprot/CP46A_HUMAN CP46A_HUMAN] Involved in the turnover of cholesterol. It converts cholesterol into 24S-hydroxycholesterol and, to a lesser extent, 25-hydroxycholesterol.
-
<ref group="xtra">PMID:022859721</ref><references group="xtra"/>
+
__TOC__
-
[[Category: Cholesterol 24-hydroxylase]]
+
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Mast, N.]]
+
[[Category: Large Structures]]
-
[[Category: Pikuleva, I A.]]
+
[[Category: Mast N]]
-
[[Category: Stout, C D.]]
+
[[Category: Pikuleva IA]]
-
[[Category: Endoplasmic reticulum]]
+
[[Category: Stout CD]]
-
[[Category: Enzyme]]
+
-
[[Category: Fluvoxamine]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: P450]]
+

Current revision

Crystal Structure of Human Cytochrome P450 CYP46A1 with Fluvoxamine Bound

PDB ID 4enh

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools