4i1q
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal Structure of hBRAP1 N-BAR domain== | |
- | + | <StructureSection load='4i1q' size='340' side='right'caption='[[4i1q]], [[Resolution|resolution]] 2.53Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[4i1q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I1Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I1Q FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.53Å</td></tr> | |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i1q OCA], [https://pdbe.org/4i1q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i1q RCSB], [https://www.ebi.ac.uk/pdbsum/4i1q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i1q ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/BIN2_HUMAN BIN2_HUMAN] Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton. Modulates membrane curvature and mediates membrane tubulation. Plays a role in podosome formation. Inhibits phagocytosis.<ref>PMID:23285027</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Sanchez-Barrena MJ]] |
Current revision
Crystal Structure of hBRAP1 N-BAR domain
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