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1pu3
From Proteopedia
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| - | [[Image:1pu3.png|left|200px]] | ||
| - | + | ==The Solution NMR Structure and Dynamics of a Recombinant Onconase with Altered N-terminal and Met23 residues== | |
| - | + | <StructureSection load='1pu3' size='340' side='right'caption='[[1pu3]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1pu3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lithobates_pipiens Lithobates pipiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PU3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PU3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pu3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pu3 OCA], [https://pdbe.org/1pu3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pu3 RCSB], [https://www.ebi.ac.uk/pdbsum/1pu3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pu3 ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1pu3]] is a 1 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/RNP30_LITPI RNP30_LITPI] Basic protein with antiproliferative/cytotoxic activity against several tumor cell lines in vitro, as well as antitumor in vivo. It exhibits a ribonuclease-like activity against high molecular weight ribosomal RNA. | |
| - | == | + | == Evolutionary Conservation == |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[ | + | Check<jmol> |
| - | [[ | + | <jmolCheckbox> |
| - | [[Category: | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pu/1pu3_consurf.spt"</scriptWhenChecked> |
| - | [[Category: | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[Category: | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [[Category: | + | </jmolCheckbox> |
| - | [[Category: | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pu3 ConSurf]. |
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lithobates pipiens]] | ||
| + | [[Category: Chang CF]] | ||
| + | [[Category: Gorbatyuk VY]] | ||
| + | [[Category: Huang TH]] | ||
| + | [[Category: Tsai CK]] | ||
Current revision
The Solution NMR Structure and Dynamics of a Recombinant Onconase with Altered N-terminal and Met23 residues
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