1pl5

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[[Image:1pl5.png|left|200px]]
 
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{{STRUCTURE_1pl5| PDB=1pl5 | SCENE= }}
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==Crystal Structure Analysis of the Sir4p C-terminal Coiled Coil==
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<StructureSection load='1pl5' size='340' side='right'caption='[[1pl5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===Crystal Structure Analysis of the Sir4p C-terminal Coiled Coil===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1pl5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PL5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PL5 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_14636601}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pl5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pl5 OCA], [https://pdbe.org/1pl5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pl5 RCSB], [https://www.ebi.ac.uk/pdbsum/1pl5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pl5 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1pl5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PL5 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/SIR4_YEAST SIR4_YEAST] The proteins SIR1 through SIR4 are required for transcriptional repression of the silent mating type loci, HML and HMR. The proteins SIR2 through SIR4 repress mulitple loci by modulating chromatin structure. Involves the compaction of chromatin fiber into a more condensed form.<ref>PMID:18039933</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Chen, L.]]
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[[Category: Chen L]]
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[[Category: Murphy, G A.]]
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[[Category: Murphy GA]]
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[[Category: Pillus, L.]]
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[[Category: Pillus L]]
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[[Category: Powell, S T.]]
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[[Category: Powell ST]]
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[[Category: Schultz, S C.]]
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[[Category: Schultz SC]]
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[[Category: Spedale, E J.]]
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[[Category: Spedale EJ]]
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[[Category: Dna binding protein-transcription complex]]
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[[Category: Parallel coiled coil homodimer]]
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Current revision

Crystal Structure Analysis of the Sir4p C-terminal Coiled Coil

PDB ID 1pl5

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