This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1pl8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1pl8" [edit=sysop:move=sysop])
Current revision (08:08, 14 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1pl8.png|left|200px]]
 
-
{{STRUCTURE_1pl8| PDB=1pl8 | SCENE= }}
+
==human SDH/NAD+ complex==
-
 
+
<StructureSection load='1pl8' size='340' side='right'caption='[[1pl8]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
===human SDH/NAD+ complex===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1pl8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PL8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PL8 FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_12962626}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pl8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pl8 OCA], [https://pdbe.org/1pl8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pl8 RCSB], [https://www.ebi.ac.uk/pdbsum/1pl8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pl8 ProSAT]</span></td></tr>
-
[[1pl8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PL8 OCA].
+
</table>
-
 
+
== Function ==
-
==Reference==
+
[https://www.uniprot.org/uniprot/DHSO_HUMAN DHSO_HUMAN] Converts sorbitol to fructose. Part of the polyol pathway that plays an important role in sperm physiology. May play a role in the sperm motility by providing an energetic source for sperm (By similarity).<ref>PMID:16278369</ref>
-
<ref group="xtra">PMID:012962626</ref><references group="xtra"/>
+
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pl/1pl8_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pl8 ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: L-iditol 2-dehydrogenase]]
+
[[Category: Large Structures]]
-
[[Category: Adams, P D.]]
+
[[Category: Adams PD]]
-
[[Category: Beebe, D A.]]
+
[[Category: Beebe DA]]
-
[[Category: Chrunyk, B.]]
+
[[Category: Chrunyk B]]
-
[[Category: Cunningham, D.]]
+
[[Category: Cunningham D]]
-
[[Category: Ekstrom, J L.]]
+
[[Category: Ekstrom JL]]
-
[[Category: Griffor, M.]]
+
[[Category: Griffor M]]
-
[[Category: Kamath, A.]]
+
[[Category: Kamath A]]
-
[[Category: Lee, S E.]]
+
[[Category: Lee SE]]
-
[[Category: Madura, R.]]
+
[[Category: Madura R]]
-
[[Category: Mcguire, D.]]
+
[[Category: Mcguire D]]
-
[[Category: Mylari, B L.]]
+
[[Category: Mylari BL]]
-
[[Category: Oates, P J.]]
+
[[Category: Oates PJ]]
-
[[Category: Pauly, T A.]]
+
[[Category: Pauly TA]]
-
[[Category: Rath, V L.]]
+
[[Category: Rath VL]]
-
[[Category: Subashi, T.]]
+
[[Category: Subashi T]]
-
[[Category: Wasilko, D.]]
+
[[Category: Wasilko D]]
-
[[Category: Watts, P.]]
+
[[Category: Watts P]]
-
[[Category: Human sorbitol dehydrogenase]]
+
-
[[Category: Nad]]
+
-
[[Category: Oxidoreductase]]
+

Current revision

human SDH/NAD+ complex

PDB ID 1pl8

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1pl8"
Personal tools