1p8t

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[[Image:1p8t.png|left|200px]]
 
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{{STRUCTURE_1p8t| PDB=1p8t | SCENE= }}
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==Crystal structure of Nogo-66 Receptor==
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<StructureSection load='1p8t' size='340' side='right'caption='[[1p8t]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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===Crystal structure of Nogo-66 Receptor===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1p8t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P8T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P8T FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12839991}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p8t OCA], [https://pdbe.org/1p8t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p8t RCSB], [https://www.ebi.ac.uk/pdbsum/1p8t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p8t ProSAT]</span></td></tr>
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[[1p8t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P8T OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/RTN4R_HUMAN RTN4R_HUMAN] Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Acts in conjunction with RTN4 and LIGO1 in regulating neuronal precursor cell motility during cortical development (By similarity).<ref>PMID:12037567</ref> <ref>PMID:14966521</ref>
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<ref group="xtra">PMID:012839991</ref><ref group="xtra">PMID:016342940</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p8/1p8t_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p8t ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Barton, W A.]]
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[[Category: Large Structures]]
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[[Category: Cate, R.]]
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[[Category: Barton WA]]
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[[Category: Fournier, A E.]]
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[[Category: Cate R]]
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[[Category: Jeffrey, P D.]]
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[[Category: Fournier AE]]
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[[Category: Liu, B P.]]
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[[Category: Jeffrey PD]]
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[[Category: Nikolov, D B.]]
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[[Category: Liu BP]]
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[[Category: Sah, D.]]
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[[Category: Nikolov DB]]
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[[Category: Strittmatter, S M.]]
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[[Category: Sah D]]
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[[Category: Tzvetkova, D.]]
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[[Category: Strittmatter SM]]
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[[Category: Ngr]]
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[[Category: Tzvetkova D]]
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[[Category: Nogo-66]]
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[[Category: Signaling protein]]
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Current revision

Crystal structure of Nogo-66 Receptor

PDB ID 1p8t

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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