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1ptm

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[[Image:1ptm.png|left|200px]]
 
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{{STRUCTURE_1ptm| PDB=1ptm | SCENE= }}
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==Crystal structure of E.coli PdxA==
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<StructureSection load='1ptm' size='340' side='right'caption='[[1ptm]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
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===Crystal structure of E.coli PdxA===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ptm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PTM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PTM FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12896974}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ptm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ptm OCA], [https://pdbe.org/1ptm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ptm RCSB], [https://www.ebi.ac.uk/pdbsum/1ptm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ptm ProSAT], [https://www.topsan.org/Proteins/BSGI/1ptm TOPSAN]</span></td></tr>
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[[1ptm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PTM OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/PDXA_ECOLI PDXA_ECOLI] Catalyzes the NAD(P)-dependent oxidation of 4-(phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).[REFERENCE:5]<ref>PMID:15026039</ref>
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<ref group="xtra">PMID:012896974</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Category: 4-hydroxythreonine-4-phosphate dehydrogenase]]
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pt/1ptm_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ptm ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: BSGI, Montreal-Kingston Bacterial Structural Genomics Initiative.]]
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[[Category: Large Structures]]
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[[Category: Banks, J.]]
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[[Category: Banks J]]
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[[Category: Cane, D E.]]
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[[Category: Cane DE]]
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[[Category: Cygler, M.]]
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[[Category: Cygler M]]
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[[Category: Li, Y.]]
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[[Category: Li Y]]
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[[Category: Matte, A.]]
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[[Category: Matte A]]
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[[Category: Sivaraman, J.]]
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[[Category: Sivaraman J]]
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[[Category: Bsgi]]
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[[Category: Crystal strucrure]]
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[[Category: Montreal-kingston bacterial structural genomics initiative]]
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[[Category: Oxidoreductase]]
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[[Category: Pdxa]]
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[[Category: Plp]]
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[[Category: Pyridoxal 5'-phosphate biosynthesis]]
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[[Category: Structural genomic]]
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Current revision

Crystal structure of E.coli PdxA

PDB ID 1ptm

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