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3unw

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[[Image:3unw.png|left|200px]]
 
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{{STRUCTURE_3unw| PDB=3unw | SCENE= }}
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==Crystal Structure of Human GAC in Complex with Glutamate==
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<StructureSection load='3unw' size='340' side='right'caption='[[3unw]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
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===Crystal Structure of Human GAC in Complex with Glutamate===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3unw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UNW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UNW FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22049910}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.56&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3unw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3unw OCA], [https://pdbe.org/3unw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3unw RCSB], [https://www.ebi.ac.uk/pdbsum/3unw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3unw ProSAT]</span></td></tr>
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[[3unw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UNW OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GLSK_HUMAN GLSK_HUMAN] Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity.
==See Also==
==See Also==
*[[Glutaminase|Glutaminase]]
*[[Glutaminase|Glutaminase]]
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*[[Glutaminase 3D structures|Glutaminase 3D structures]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:022049910</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Glutaminase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Cheng, F.]]
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[[Category: Large Structures]]
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[[Category: DeLaBarre, B.]]
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[[Category: Cheng F]]
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[[Category: Gao, Y.]]
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[[Category: DeLaBarre B]]
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[[Category: Gross, S.]]
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[[Category: Gao Y]]
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[[Category: Hurov, J.]]
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[[Category: Gross S]]
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[[Category: Jha, A.]]
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[[Category: Hurov J]]
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[[Category: Jiang, F.]]
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[[Category: Jha A]]
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[[Category: Song, J J.]]
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[[Category: Jiang F]]
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[[Category: Wie, W.]]
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[[Category: Song JJ]]
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[[Category: Alpha/beta]]
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[[Category: Wie W]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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Current revision

Crystal Structure of Human GAC in Complex with Glutamate

PDB ID 3unw

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