1t3h

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[[Image:1t3h.gif|left|200px]]<br /><applet load="1t3h" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1t3h, resolution 2.50&Aring;" />
 
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'''X-ray Structure of Dephospho-CoA Kinase from E. coli Norteast Structural Genomics Consortium Target ER57'''<br />
 
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==About this Structure==
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==X-ray Structure of Dephospho-CoA Kinase from E. coli Norteast Structural Genomics Consortium Target ER57==
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1T3H is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Dephospho-CoA_kinase Dephospho-CoA kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.24 2.7.1.24] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T3H OCA].
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<StructureSection load='1t3h' size='340' side='right'caption='[[1t3h]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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[[Category: Dephospho-CoA kinase]]
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1t3h]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T3H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T3H FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t3h OCA], [https://pdbe.org/1t3h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t3h RCSB], [https://www.ebi.ac.uk/pdbsum/1t3h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t3h ProSAT], [https://www.topsan.org/Proteins/NESGC/1t3h TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/COAE_ECOLI COAE_ECOLI] Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t3/1t3h_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t3h ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Acton, T.]]
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[[Category: Acton T]]
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[[Category: Benach, J.]]
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[[Category: Benach J]]
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[[Category: Chen, Y.]]
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[[Category: Chen Y]]
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[[Category: Edstrom, W.]]
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[[Category: Edstrom W]]
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[[Category: Forouhar, F.]]
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[[Category: Forouhar F]]
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[[Category: Hunt, J.]]
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[[Category: Hunt J]]
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[[Category: Kuzin, A P.]]
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[[Category: Kuzin AP]]
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[[Category: Ma, L C.]]
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[[Category: Ma L-C]]
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[[Category: Montelione, G.]]
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[[Category: Montelione G]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Shastry R]]
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[[Category: Shastry, R.]]
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[[Category: Tong L]]
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[[Category: Tong, L.]]
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[[Category: Vorobiev S]]
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[[Category: Vorobiev, S.]]
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[[Category: Xia R]]
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[[Category: Xia, R.]]
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[[Category: SO4]]
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[[Category: nesg]]
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[[Category: northeast structural genomics consortium]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomics]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:09:26 2008''
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Current revision

X-ray Structure of Dephospho-CoA Kinase from E. coli Norteast Structural Genomics Consortium Target ER57

PDB ID 1t3h

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