4goy

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:52, 14 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:4goy.png|left|200px]]
 
-
{{STRUCTURE_4goy| PDB=4goy | SCENE= }}
+
==The crystal structure of human fascin 1 K41A mutant==
 +
<StructureSection load='4goy' size='340' side='right'caption='[[4goy]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[4goy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GOY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GOY FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4goy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4goy OCA], [https://pdbe.org/4goy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4goy RCSB], [https://www.ebi.ac.uk/pdbsum/4goy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4goy ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/FSCN1_HUMAN FSCN1_HUMAN] Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.<ref>PMID:9362073</ref> <ref>PMID:9571235</ref> <ref>PMID:20137952</ref> <ref>PMID:20393565</ref>
-
===The crystal structure of human fascin 1 K41A mutant===
+
==See Also==
-
 
+
*[[Fascin|Fascin]]
-
{{ABSTRACT_PUBMED_23184945}}
+
== References ==
-
 
+
<references/>
-
==About this Structure==
+
__TOC__
-
[[4goy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GOY OCA].
+
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Chen, L.]]
+
[[Category: Large Structures]]
-
[[Category: Chen, S.]]
+
[[Category: Chen L]]
-
[[Category: Diaz-Avalos, R.]]
+
[[Category: Chen S]]
-
[[Category: Huang, F K.]]
+
[[Category: Diaz-Avalos R]]
-
[[Category: Huang, J.]]
+
[[Category: Huang FK]]
-
[[Category: Huang, X Y.]]
+
[[Category: Huang J]]
-
[[Category: Jakoncic, J.]]
+
[[Category: Huang XY]]
-
[[Category: Leo-Macias, A.]]
+
[[Category: Jakoncic J]]
-
[[Category: Yang, S Y.]]
+
[[Category: Leo-Macias A]]
-
[[Category: Zhang, J J.]]
+
[[Category: Yang SY]]
-
[[Category: Actin]]
+
[[Category: Zhang JJ]]
-
[[Category: Actin bundling protein]]
+
-
[[Category: Actin-binding]]
+
-
[[Category: Beta-trefoil]]
+
-
[[Category: Cancer]]
+
-
[[Category: Cell migration]]
+
-
[[Category: Metastasis]]
+
-
[[Category: Phosphoprotein]]
+
-
[[Category: Protein binding]]
+

Current revision

The crystal structure of human fascin 1 K41A mutant

PDB ID 4goy

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4goy"
Personal tools