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3uo9
From Proteopedia
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| - | [[Image:3uo9.png|left|200px]] | ||
| - | + | ==Crystal Structure of Human GAC in Complex with Glutamate and BPTES== | |
| - | + | <StructureSection load='3uo9' size='340' side='right'caption='[[3uo9]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3uo9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UO9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UO9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=04A:N,N-[SULFANEDIYLBIS(ETHANE-2,1-DIYL-1,3,4-THIADIAZOLE-5,2-DIYL)]BIS(2-PHENYLACETAMIDE)'>04A</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uo9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uo9 OCA], [https://pdbe.org/3uo9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uo9 RCSB], [https://www.ebi.ac.uk/pdbsum/3uo9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uo9 ProSAT]</span></td></tr> |
| - | [[3uo9]] is a 4 chain structure with sequence from [ | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GLSK_HUMAN GLSK_HUMAN] Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. | ||
==See Also== | ==See Also== | ||
| - | *[[Glutaminase|Glutaminase]] | + | *[[Glutaminase 3D structures|Glutaminase 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | + | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Cheng | + | [[Category: Large Structures]] |
| - | [[Category: DeLaBarre | + | [[Category: Cheng F]] |
| - | [[Category: Gao | + | [[Category: DeLaBarre B]] |
| - | [[Category: Gross | + | [[Category: Gao Y]] |
| - | [[Category: Hurov | + | [[Category: Gross S]] |
| - | [[Category: Jha | + | [[Category: Hurov JB]] |
| - | [[Category: Jiang | + | [[Category: Jha A]] |
| - | [[Category: Song | + | [[Category: Jiang F]] |
| - | [[Category: Wei | + | [[Category: Song JJ]] |
| - | + | [[Category: Wei W]] | |
Current revision
Crystal Structure of Human GAC in Complex with Glutamate and BPTES
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Categories: Homo sapiens | Large Structures | Cheng F | DeLaBarre B | Gao Y | Gross S | Hurov JB | Jha A | Jiang F | Song JJ | Wei W
