This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2m28
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2m28 is ON HOLD Authors: Ames, J.B. Description: NMR structure of Ca2+ bound CaBP4 C-domain) |
|||
| (11 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==NMR structure of Ca2+ bound CaBP4 C-domain== | |
| - | + | <StructureSection load='2m28' size='340' side='right'caption='[[2m28]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2m28]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M28 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m28 OCA], [https://pdbe.org/2m28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m28 RCSB], [https://www.ebi.ac.uk/pdbsum/2m28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m28 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CABP4_MOUSE CABP4_MOUSE] Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages.<ref>PMID:15452577</ref> <ref>PMID:16249514</ref> <ref>PMID:17050707</ref> <ref>PMID:17947313</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Ames JB]] | ||
Current revision
NMR structure of Ca2+ bound CaBP4 C-domain
| |||||||||||
