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1t70
From Proteopedia
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| - | [[Image:1t70.gif|left|200px]]<br /><applet load="1t70" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1t70, resolution 2.30Å" /> | ||
| - | '''Crystal structure of a novel phosphatase from Deinococcus radiodurans'''<br /> | ||
| - | == | + | ==Crystal structure of a novel phosphatase from Deinococcus radiodurans== |
| - | + | <StructureSection load='1t70' size='340' side='right'caption='[[1t70]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | [[ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[1t70]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans_R1 Deinococcus radiodurans R1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T70 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T70 FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t70 OCA], [https://pdbe.org/1t70 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t70 RCSB], [https://www.ebi.ac.uk/pdbsum/1t70 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t70 ProSAT], [https://www.topsan.org/Proteins/BSGC/1t70 TOPSAN]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/PPDE_DEIRA PPDE_DEIRA] Has a dual activity phosphatase/phosphodiesterase in vitro, with a preference to phosphoenolpyruvate (PEP) and 2',3'-cAMP, respectively. Can also use 2',3'-cGMP, 2',3'-cCMP and various model substrates such as p-nitrophenyl phosphate (pNPP), bis-p-nitrophenyl phosphate (bis-pNPP) and p-nitrophenyl thymidine monophosphate (pNP-TMP).<ref>PMID:17847097</ref> |
| - | [[Category: | + | == Evolutionary Conservation == |
| - | [[Category: | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[Category: | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t7/1t70_consurf.spt"</scriptWhenChecked> | |
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t70 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Deinococcus radiodurans R1]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Kim R]] | ||
| + | [[Category: Kim SH]] | ||
| + | [[Category: Shin DH]] | ||
| + | [[Category: Wang W]] | ||
| + | [[Category: Yokota H]] | ||
Current revision
Crystal structure of a novel phosphatase from Deinococcus radiodurans
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